1. Illegible text. I can’t read that, it’s too small. And what on earth is that font called?
2. Busy backgrounds. Oh MySpace, why do you allow users to create profiles like that? My eyes hurt.
3. Obscure links. I’m confused, can I click on that or not? Oh I get it, you don’t want me to view other pages.
4. Flyouts that are too large. Holy crap Yahoo! This is a page within a flyout!
5. Drop-down menu navigation too many levels deep. OK, if I slowly move my mouse this way first… dammit Jim, I’m a doctor not a magician!
6. Complicated navigation. I just want to get to that page, the one over there! Oh I see, you want me to complete the maze first.